New tool may save lives by predicting risk of heart attack and stroke (study)
A new risk calculator that can better predict people at high risk for heart and circulatory disease years before they strike is ready for use in the UK and Europe, the researchers say.
The risk calculator, SCORE2, allows physicians to more accurately predict who is at risk for a heart attack or stroke over the next 10 years.
Researchers say the tool will help save people from a potentially fatal heart attack or stroke, saving lives.
People reported to be at increased risk may be put on personalized preventive therapy, such as statins, or will be given lifestyle advice to reduce their risk.
About 200 investigators and researchers across Europe analyzed data from nearly 700,000 participants – mostly middle-aged – from 45 different studies.
When recruited for the studies, participants had no history of heart and circulatory disease, and over the 10 years of follow-up, 30,000 had a cardiovascular event, including a heart attack or stroke. fatal or non-fatal.
The risk tool was statistically recalibrated, using cardiovascular and risk factor data specific to the region of 10.8 million people, to more accurately estimate cardiovascular risk for populations divided into four European risk regions.
It uses known risk factors for heart and circulatory disease such as age, gender, cholesterol, blood pressure, and smoking.
The calculator takes into account current trends in heart and circulatory disease, can predict fatal and non-fatal conditions, and adapts to countries with different levels of risk.
Researchers say it can better estimate cardiovascular risk in young people and improve how treatment is tailored to older people and those in high-risk areas across Europe.
Professor Emanuele Di Angelantonio, BHF-funded researcher at Cambridge University’s BHF Center of Excellence for Research, said: “This risk management tool is much more powerful and superior than what physicians have been using for decades. .
“It will fit perfectly into current prevention programs with substantial real-world impact by improving the prevention of cardiovascular disease across Europe before it strikes. “
Professor Sir Nilesh Samani, British Heart Foundation medical director and cardiologist, said: ‘This new risk tool is a major breakthrough and will save many more people from heart attacks, strokes and heart disease, which all develop silently for many years. and strike without warning.
“It will be the new golden standard for physicians to determine which patients are most at risk for these conditions, and enable personalized treatment and lifestyle advice much sooner.”
SCORE2 will be adopted by the next European guidelines on the prevention of cardiovascular diseases in clinical practice.
The research was funded by the British Heart Foundation and published in the European Heart Journal.